After years of “unexplained” recurrent miscarriage, I was finally diagnosed with MTHFR C677T.
The MTHFR gene provides instructions for producing an enzyme called methylenetetrahydrofolate reductase, which plays a critical role in the process of methylation, a biochemical pathway involved in DNA synthesis and repair, detoxification, hormone metabolism, neurotransmitter production, and energy regulation.
Certain MTHFR gene variants, such as C677T and A1298C, can reduce the efficiency of this enzyme. If you have one copy of MTHFR, it’s a 40% reduction in methylation(ability for the body to detox). 2 copies means 70% reduction in methylation or detoxification(this is what I have). This may affect the body’s ability to convert folic acid into its active form, 5-MTHF (methylfolate), which is essential for proper methylation. These variants are relatively common; it’s estimated that up to 40–50% of people may carry at least one copy of a common MTHFR variant, often without recognizing it is the root of their symptoms.
I wish I would have had this guide when I was first diagnosed and that is why I created it!
Breathe Wellness Co 